Autors: Gieva, E. E., Rusev, R. P., Angelov, G. V., Hristov, M. H., Takov, T. B.
Title: Digital operation of microelectronic circuits analogous to protein hydrogen bonding networks
Keywords: Hydrogen Bonding Networks (HBNs), Proteins, β-lactamase, Beh

Abstract: Two hydrogen bonding networks with water molecules and branching residues extracted from β-lactamase protein are investigated and their proton transfer characteristics are studied by creating analogous electrical circuits consisting of block-elements. The block-elements and their proton transfer are described by polynomials that are coded in Matlab and in Verilog-A for use in the Spectre simulator of Cadence IC design system. DC and digital pulse analyses are performed to demonstrate that some circuit outputs behave as repeaters while other – behave as inverters. The results also showed that the HBN circuits might behave as a D-latch and a demultiplexer.



    International Journal BIOautomation, vol. 16, issue 4, pp. 291-308, 2013, Bulgaria, Institute of Biophysics and Biomedical Engineering at the Bulgarian Academy of Sciences, ISSN 1314-2321

    Copyright Biomed BAS

    Full text of the publication

    Цитирания (Citation/s):
    1. R. Rusev, "Hydrogen bonding network as a logic gate," 2017 XXVI International Scientific Conference Electronics (ET), Sozopol, 2017, pp. 1-4, DOI: 10.1109/ET.2017.8124383. - 2017 - в издания, индексирани в Scopus или Web of Science

    Вид: статия в списание, публикация в издание с импакт фактор, публикация в реферирано издание, индексирана в Scopus