Autors: Neznakomova, M. P., Dineff P., Shopov, M. D., Nikolov, N. D., Gospodinova, D. N.
Title: Geometric Analysis and Modeling of Electrospun Nanofiber Mat Deposition in a Top-Down Vertical Configuration
Keywords: electrospinning, geometric modeling, nanofiber mat geometry, nanofibers, process parameters, PVA, statistical analysis, three-dimensional reconstruction

Abstract: Electrospinning is a widely used technique for fabricating nanomaterials with tailored morphology and functional properties. This study investigates how two fundamental process parameters—applied voltage and needle tip-to-collector distance—affect the spatial geometry and deposited mass of electrospun nanofiber mats in a top-down vertical electrospinning setup using a 10% (w/v) PVA solution prepared in deionized water. To support this hypothesis, both experimental measurements and 3D geometric modeling were performed to evaluate the area, perimeter, and deposited mass under different parameter combinations. Digital image analysis and cross-sectional reconstruction were applied to model nanofiber deposition. Regression and ANOVA analyses reveal that the tip-to-collector distance has a statistically significant impact on both area and perimeter of the electrospun nanofiber mat, while the applied voltage in the tested range (15–20 kV) has no significant effect. Interestingly, the total deposited mass shows no clear dependence on either parameter, likely due to startup irregularities or solution droplets.

References

  1. Barhoum A. Pal K. Rahier H. Uludag H. Kim I.S. Bechelany M. Nanofibers as new-generation materials: From spinning and nano-spinning fabrication techniques to emerging applications Appl. Mater. Today 2019 17 1 35 10.1016/j.apmt.2019.06.015
  2. Xu H. Yagi S. Ashour S. Du L. Hoque E. Tan L. A Review on Current Nanofiber Technologies: Electrospinning, Centrifugal Spinning, and Electro-Centrifugal Spinning Macromol. Mater. Eng. 2023 308 2200502 10.1002/mame.202200502
  3. Xue J. Wu T. Dai Y. Xia Y. Electrospinning and Electrospun Nanofibers: Methods, Materials, and Applications Chem. Rev. 2019 119 5298 5415 10.1021/acs.chemrev.8b00593
  4. Alghoraibi I. Alomari S. Different Methods for Nanofiber Design and Fabrication Handbook of Nanofibers Springer Cham, Switzerland 2018 1 46
  5. Reddy V.S. Tian Y. Zhang C. Ye Z. Roy K. Chinnappan A. Ramakrishna S. Liu W. Ghosh R. A Review on Electrospun Nanofibers Based Advanced Applications: From Health Care to Energy Devices Polymers 2021 13 3746 10.3390/polym13213746 34771302
  6. Teo W.-E. Inai R. RamaKrishnaan S. Technological advances in electrospinning of nanofibers Sci. Technol. Adv. Mater. 2011 12 013002 10.1088/1468-6996/12/1/013002 27877375
  7. Gugulothu D. Barhoum A. Afzal S.M. Venkateshwarlu B. Uludag H. Structural Multifunctional Nanofibers and Their Emerging Applications Handbook of Nanofibers Barhoum A. Bechelany M. Makhlouf A.S.H. Springer International Publishing Cham, Switzerland 2019 693 732
  8. Borban B. Gohain M.B. Yadav D. Karki S. Ingole P.G. Nano-electrospun membranes: Green solutions for diverse industrial needs J. Hazard. Mater. Adv. 2023 12 100373 10.1016/j.hazadv.2023.100373
  9. Vanaraj R. Arumugam B. Mayakrishnan G. Kim I.S. Kim S.C. A Review on Electrospun Nanofiber Composites for an Efficient Electrochemical Sensor Applications Sensors 2023 23 6705 10.3390/s23156705
  10. Guo F. Ren Z. Wang S. Xie Y. Pan J. Huang J. Zhu T. Cheng S. Lai Y. Recent Progress of Electrospun Nanofiber-Based Composite Materials for Monitoring Physical, Physiological, and Body Fluid Signals Nano-Micro Lett. 2025 17 302 10.1007/s40820-025-01804-2
  11. Sumathi S. A review of electrospun polymeric fibers as potential drug delivery systems for tunable release kinetics J. Sci. Adv. Mater. Devices 2025 10 100933 10.1016/j.jsamd.2025.100933
  12. Abdulhussain R. Adebisi A. Conway B.R. Asare-Addo K. Electrospun nanofibers: Exploring process parameters, polymer selection, and recent applications in pharmaceuticals and drug delivery J. Drug Deliv. Sci. Technol. 2023 90 105156 10.1016/j.jddst.2023.105156
  13. Suresh S. Becker A. Glasmacher B. Impact of Apparatus Orientation and Gravity in Electrospinning—A Review of Empirical Evidence Polymers 2020 12 2448 10.3390/polym12112448
  14. Caloian I. Trapp J. Williams M.W. Kim R.A. Moustafa M.E. Stwodah E.H. Tang C. Direct Fabrication of Functional Shapes on 3D Surfaces Using Electrospinning Polymers 2023 15 533 10.3390/polym15030533
  15. Zare M. Davoodi P. Ramakrishna S. Electrospun Shape Memory Polymer Micro-/Nanofibers and Tailoring Their Roles for Biomedical Applications Nanomaterials 2021 11 933 10.3390/nano11040933
  16. Lu Z. Zhou Q. Wei Z. Xu L. Peng S. Zeng W. Synthesis of Hollow Nanofibers and Application on Detecting SF6 Decomposing Products Front. Mater. 2019 6 183 10.3389/fmats.2019.00183
  17. Li L. Peng S. Lee J.K.Y. Ji D. Srinivasan M. Ramakrishna S. Electrospun hollow nanofibers for advanced secondary batteries Nano Energy 2017 39 111 139 10.1016/j.nanoen.2017.06.050
  18. Homaeigohar S. Davoudpour Y. Habibi Y. Elbahri M. The Electrospun Ceramic Hollow Nanofibers Nanomaterials 2017 7 383 10.3390/nano7110383
  19. Chiang Y.-C. Chin W.-T. Huang C.-C. The Application of Hollow Carbon Nanofibers Prepared by Electrospinning to Carbon Dioxide Capture Polymers 2021 13 3275 10.3390/polym13193275 34641091
  20. Li P. Ma X. Liu F. Zhao Y.L. Ding Y. Yang J. Synthesis of highly ordered mesoporous carbons nanofiber web based on electrospinning strategy for supercapacitor Microporous Mesoporous Mater. 2020 305 110283 10.1016/j.micromeso.2020.110283
  21. El-Rafei A.M. Synthesis and characterization of high surface area mesoporous manganese oxides nanofibers prepared by electrospinning technique J. Aust. Ceram. Soc. 2023 59 633 643 10.1007/s41779-023-00862-2
  22. Zupančič Š. Core-shell nanofibers as drug delivery systems Acta Pharm. 2019 69 131 153 10.2478/acph-2019-0014
  23. Abdullah M.F. Nuge T. Andriyana A. Ang B.C. Muhamad F. Core–Shell Fibers: Design, Roles, and Controllable Release Strategies in Tissue Engineering and Drug Delivery Polymers 2019 11 2008 10.3390/polym11122008
  24. Ge R. Ji Y. Ding Y. Huang C. He H. Yu D.-G. Electrospun self-emulsifying core-shell nanofibers for effective delivery of paclitaxel Front. Bioeng. Biotechnol. 2023 11 1112338 10.3389/fbioe.2023.1112338 36741747
  25. Huang Y. Li Y. Zhang Y. Yu H. Tan Z. Near-field electrospinning for 2D and 3D structuring: Fundamentals, methods, and applications Mater. Today Adv. 2024 21 100461 10.1016/j.mtadv.2023.100461
  26. Langwald S.V. Ehrmann A. Sabantina L. Measuring Physical Properties of Electrospun Nanofiber Mats for Different Biomedical Applications Membranes 2023 13 488 10.3390/membranes13050488
  27. Iranshahi K. Defraeye T. Rossi R.M. Müller U.C. Electrohydrodynamics and its applications: Recent advances and future perspectives Int. J. Heat Mass Transf. 2024 232 125895 10.1016/j.ijheatmasstransfer.2024.125895
  28. “Introductory Tutorial for Electrospinning,” QINGZI NANO Available online: https://www.nanofiberlabs.com/solutions/introductory-tutorial-for-electrospinning.html?utm_source=chatgpt.com (accessed on 28 July 2025)
  29. Lauricella M. Pisignano D. Succi S. Three-Dimensional Model for Electrospinning Processes in Controlled Gas Counterflow J. Phys. Chem. A 2016 120 4884 4892 10.1021/acs.jpca.5b12450
  30. Lauricella M. Succi S. Zussman E. Pisignano D. Yarin A.L. Models of polymer solutions in electrified jets and solution blowing Rev. Mod. Phys. 2020 92 035004 10.1103/RevModPhys.92.035004
  31. Singh A.K. Choubey A. Srivastava R.K. Bahga S.S. Physics of moderately stretched electrified jets in electrohydrodynamic jet printing Phys. Rev. E 2023 107 045103 10.1103/PhysRevE.107.045103
  32. Chan K.C. Sadaf A. Korvink J.G. Wenzel W. Electromechanical analysis of electrospun polymer fiber deposition J. Appl. Phys. 2023 134 184902 10.1063/5.0171903
  33. Guo Y. Wang X. Shen Y. Dong K. Shen L. Alzalab A.A.A. Research progress, models and simulation of electrospinning technology: A review J. Mater. Sci. 2022 57 58 104 10.1007/s10853-021-06575-w
  34. Xue J. Wang Z. Chen Y. Wang J. Xu H. Li B. Dong Q. Wang J. The critical threshold and bending dynamics of whipping instability in cone-jet electrospray Chem. Eng. Sci. 2026 322 123101 10.1016/j.ces.2025.123101
  35. Liu J. Dong S. Liu Y. Pan S. Yin Z. Fluid and Electric Field Simulation and Optimization of the Multi-Vane and Multi-Slit Electrospinning Nozzle Nanomaterials 2025 15 461 10.3390/nano15060461
  36. Shabani A. Al G.A. Berri N. Castro-Dominguez B. Leese H.S. Martinez-Hernandez U. Electrospinning Technology, Machine Learning, and Control Approaches: A Review Adv. Eng. Mater. 2025 27 2401353 10.1002/adem.202401353
  37. Liu J. Dong S. Wang C. Liu Y. Pan S. Yin Z. Research on Electric Field Homogenization in Radial Multi-Nozzle Electrospinning Nanomaterials 2024 14 1199 10.3390/nano14141199
  38. Wen X. Xiong J. Lei S. Wang L. Qin X. Diameter Refinement of Electrospun Nanofibers: From Mechanism, Strategies to Applications Adv. Fiber Mater. 2021 4 145 161 10.1007/s42765-021-00113-8
  39. Dong K. Zan G. Mao X. Zhou H. Wang H. Wu Q. Wu T. A conductive folding metamaterial via laser-induced biomimetic electrospinning Proc. Natl. Acad. Sci. USA 2025 122 e2516066122 10.1073/pnas.2516066122 41171851
  40. Ryu H.I. Koo M.S. Kim S. Kim S. Park Y.-A. Park S.M. Uniform-thickness electrospun nanofiber mat production system based on real-time thickness measurement Sci. Rep. 2020 10 20847 10.1038/s41598-020-77985-0
  41. Reneker D.H. Yarin A.L. Electrospinning jets and polymer nanofibers Polymer 2008 49 2387 2425 10.1016/j.polymer.2008.02.002
  42. SalehHudin H.S. Mohamad E.N. Mahadi W.N.L. Afifi A.M. Multiple-jet electrospinning methods for nanofiber processing: A review Mater. Manuf. 2018 33 479 498 10.1080/10426914.2017.1388523
  43. Subeshan B. Atayo A. Asmatulu E. Machine learning applications for electrospun nanofibers: A review J. Mater. Sci. 2024 59 14095 14140 10.1007/s10853-024-09994-7
  44. Duan Y. Kalluri L. Satpathy M. Effect of Electrospinning Parameters on the Fiber Diameter and Morphology of PLGA Nanofibers Dent. Oral Biol. Craniofacial Res. 2021 4 10.31487/j.DOBCR.2021.02.04 36970249
  45. Pillay V. Dott C. Choonara Y.E. Tyagi C. Tomar L. Kumar P. Du Toit L.C. Ndesendo V.M.K. A Review of the Effect of Processing Variables on the Fabrication of Electrospun Nanofibers for Drug Delivery Applications J. Nanomater. 2013 2013 789289 10.1155/2013/789289
  46. Haider A. Haider S. Kang I.-K. A comprehensive review summarizing the effect of electrospinning parameters and potential applications of nanofibers in biomedical and biotechnology Arab. J. Chem. 2015 11 1165 1188 10.1016/j.arabjc.2015.11.015
  47. Can-Herrera L.A. Oliva A.I. Dzul-Cervantes M.A.A. Pacheco-Salazar O.F. Cervantes-Uc J.M. Morphological and Mechanical Properties of Electrospun Polycaprolactone Scaffolds: Effect of Applied Voltage Polymers 2021 13 662 10.3390/polym13040662
  48. Beachley V. Wen X. Effect of electrospinning parameters on the nanofiber diameter and length Mater. Sci. Eng. C 2009 29 663 668 10.1016/j.msec.2008.10.037
  49. Nayak R. Padhye R. Arnold L. 2-Melt-electrospinning of nanofibers Electrospun Nanofibers Afshari M. Woodhead Publishing Series in Textiles Woodhead Publishing Cambridge, UK 2017 11 40 10.1016/B978-0-08-100907-9.00002-7
  50. Peijs T. 6.7 Electrospun Polymer Nanofibers and Their Composites Comprehensive Composite Materials II Beaumont W.R. Zweben C.H. Elsevier Oxford, UK 2018 162 200 10.1016/B978-0-12-803581-8.10025-6
  51. Mehta P.P. Pawar V.S. 22-Electrospun nanofiber scaffolds: Technology and applications Applications of Nanocomposite Materials in Drug Delivery Inamuddin Asiri A.M. Mohammad A. Woodhead Publishing Series in Biomaterials Woodhead Publishing Cambridge, UK 2018 509 573 10.1016/B978-0-12-813741-3.00023-6
  52. Yang Z. Gao M. Liang W. Ao T. Chen W. One-dimensional electrospinning nanomaterials toward capacitive deionization: Fundamentals, development, and perspectives Desalination 2023 567 117010 10.1016/j.desal.2023.117010
  53. Moyo D. Patanaik A. Anandjiwala R. 12-Process control in nonwovens production Process Control in Textile Manufacturing Majumdar A. Das A. Alagirusamy R. Kothari V.K. Woodhead Publishing Series in Textiles Woodhead Publishing Cambridge, UK 2013 279 299 10.1533/9780857095633.3.279

Issue

Nanomaterials, vol. 16, 2026, Albania, https://doi.org/10.3390/nano16020126

Copyright MDPI

Вид: статия в списание, публикация в издание с импакт фактор, публикация в реферирано издание, индексирана в Scopus и Web of Science