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Технически университет - София

Abstract: Diabetic retinopathy is a chronic medical condition characterized by damage to the retina caused by the presence of diabetes. It is a microangiopathy, which in the early stages is caused by vascular occlusion, and in its late stages is expressed in fibrovascular proliferation. Vascular occlusion, leading to increased vascular permeability and narrowing or blockage of vessels supplying the retina, is expressed by a blood-retinal barrier. Diabetic retinopathy is among the leading causes of blindness among the working population aged up to 75 years. Retinopathy is a common concomitant symptom in the presence of diabetes mellitus and develops in almost 90% of patients with diabetes mellitus regardless of the type of the disease. Since diabetic retinopathy is the basis of approximately 10-15% of newly diagnosed cases of blindness annually, its social importance requires the development of innovative methods for its treatment and cure.

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