|Autors: Райкова Р., Маринкова Д., Iliev, I. T.|
Title: Quartz crystal microbalance detection of aflatoxin B1 by self-assembled monolayer technique
Keywords: QCM, biosensors
Abstract: New biosensor techniques allowing detection of low concentrated substances show a great variety nowadays. The construction of a system with modified quartz as a part of a Quartz Crystal Microbalance (QCM) techniques helps the detection and confirmation of low toxin concentrations in a sample. Objective: The study aims to allow the application of methods for preparation and modification of the gold surface of piezoelectric crystal for detection of aflatoxin B1(AFB1) in the concentration range 0.2-2.0 µg/L by QCM technique (quartz-crystal microbalance). Methods: The procedure for the preparation of quartz crystal sensors for experimental purposes was performed. The quartz surface was activated and covered with self-assembled monolayer to immobilize antibody (rabbit anti-aflatoxin B1) for the detection of antigen-antibody reaction.
Copyright Bentham Science Publishers
Вид: статия в списание, публикация в издание с импакт фактор, публикация в реферирано издание