Autors: Ivanova, N. V., Godjevargova Tz., Ivanova D., Gabrovska K. Title: Application of immobilized horseradish peroxidase onto modified acrylonitrile copolymer membrane in removing of phenol from water Keywords: Membranes Horseradishperoxidase Immobilization Application Abstract: A non-modifiedandmodifiedwithNaOHandethylenediamineultrafiltrationmembranespreparedfrom ANcopolymerhavebeenusedascarriersfortheimmobilizationofhorseradishperoxidase(HRP)enzyme. The amountofboundproteinontothemembranesandtheactivityoftheimmobilizedenzymehavebeen investigatedaswellasthepHandthermaloptimum,andthethermalstabilityofthefreeandimmobilized HRP.Theexperimentshaveprovedthatthemodifiedmembraneisabettersupportfortheimmobilization of HRPenzyme.Thelatterhasshownagreaterthermalstabilitythanthefreeenzyme. A possibleapplicationhasbeenstudiedforreducingphenolconcentrationinwatersolutionsthrough oxidationofphenolbyhydrogenperoxide,inthepresenceoffreeandimmobilizedHRPenzymeon modifiedANcopolymermembranes.Ahigherdegreeofthephenoloxidationhasbeenobservedinthe presenceoftheimmobilizedenzyme.Atotalremovalofphenolhasbeenachievedinthepresenceof immobilizedHRPatconcentrationofthehydrogenperoxide0.5mmolL−1 and concentrationofthephenol in themodelsolutionswithintheinterval5–40mgL−1. Ahighdegreeof References Issue
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