Autors: T. G. Vladkova., A. D. Staneva., I. A. Avramova., I. A. Ivanova., Gospodinova, D. N.
Title: Fucoidan-Containing, Low-Adhesive Siloxane Coatings for Medical Applications: Inhibition of Bacterial Growth and Biofilm Development
Keywords: The deposition of low-adhesive siloxane coatings is a curren

Abstract: The deposition of low-adhesive siloxane coatings is a current trend for the non-toxic control of bacterial growth and biofilm formation. Total elimination of biofilm formation has not been reported so far. The aim of this investigation was to study the ability of a non-toxic, natural, biologically active substance, such as fucoidan, to inhibit bacterial growth on similar medical coatings. The fucoidan amount was varied, and its impact on the bioadhesion-influencing surface characteristics, as well as on bacterial cell growth, was investigated. The inclusion of up to 3–4 wt.% brown algae-derived fucoidan in the coatings increases their inhibitory effect, more significantly on the Gram-positive bacterium S. aureus than on the Gram-negative bacterium Escherichia coli. The biological activity of the studied siloxane coatings was ascribed to the formation of a low-adhesive, biologically active surface top layer consisting of siloxane oil and dispersed water-soluble fucoidan particles. This

References

    Issue

    Materials, vol. 16, issue 10, pp. 3651, 2023, Switzerland, MDPI, DOI 10.3390/ma16103651

    Copyright MDPI

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    Цитирания (Citation/s):
    1. Y. Lan, K. Qin, and S. Wu, “The physiological activities of fucoidan and its application in animal breeding,” Fish & Shellfish Immunology, vol. 147, p. 109458, Apr. 2024, doi: 10.1016/j.fsi.2024.109458. - 2024 - в издания, индексирани в Scopus или Web of Science
    2. A. Roy, P. K. Roy, S. R. Cho, and S. Y. Park, “Effects of Fucoidan on the Inhibition of Biofilm Formation of Salmonella enterica Subsp. enterica Serovar Typhimurium on Seafoods and Its Molecular Antibiofilm Mechanisms,” Microorganisms, vol. 13, no. 4, Art. no. 4, Apr. 2025, doi: 10.3390/microorganisms13040914. - 2025 - в издания, индексирани в Scopus

    Вид: статия в списание, публикация в издание с импакт фактор, публикация в реферирано издание, индексирана в Scopus