| Autors: E. Pecheva., Petrov, T. S., C. Lungu., P. Montgomery., L. Pramatarova. Title: Stimulated in vitro bone-like apatite formation by a novel laser processing technique Keywords: Laser Processing, Bone-like apatite Abstract: Hydroxyapatite is a mineral widely studied as an artificial replacement material in dentistry and medicine due to its chemical and crystallographic resemblance to bone and tooth minerals. New trend of stimulating the hydroxyapatite formation in vitro has evolved by applying various sources of external energy. Lasers have been widely used in biomaterials area as clean and powerful sources of energy and have diverse bioapplications. They are excellent tools for creating micrometer-scale structures by precise and flexible irradiation of small and complex shapes. Using a hierarchical approach that mimics the natural material formation processes, we developed a method to produce materials with controlled physical structure at both micro- and nanometer scale. Materials organized on multiple length scales bear a closer resemblance to biological matrices than those with single scale features, and thus materials with multi-scale organization should be more advantageous in biomedical applicatio References Issue
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Вид: статия в списание, публикация в издание с импакт фактор, публикация в реферирано издание, индексирана в Scopus и Web of Science
