Autors: M. Dimitrova., A. Petrova., E. Pecheva,., Petrov, T. S., P. Montgomery., L. Pramatarova.
Title: Mechanical properties of extracellular matrix/hydroxyapatite composites
Keywords: Hydroxyapatite, Laser-liquid-solid-interaction

Abstract: An increasing interest in biomimetics – design of materials based on natural biological structures - has led to the nanomechanical characterization of biomaterials. In this regard, nanoindentation has been used in conjunction with the determination of the mechanical properties of the extracellular matrix (ECM) proteins that are known as ligands in reactions with cell surface receptors involved in bone physiology. The aim of the presented work is to investigate the - and nano-scale mechanical properties of laser designed extracellular matrix/hydroxyapatite composites. The osteoblast-like cell line SAOS-2 synthesised and assembled its own ECM on the solid substrates under standard cell culture conditions. After selective removal of cells, thin films of ECM on substrates of stainless steel (SS), silicon (S) and silica glass (SG) were obtained. One group of samples was soaked in simulated body fluid (SBF) and another was obtained by simultaneous immersion in the SBF and treatment by laser

References

    Issue

    Journal of Optoelectronics and Advanced Materials, vol. 9, issue 1, pp. 229-232, 2007, Hungary,

    Цитирания (Citation/s):
    1. Peng, Fei, Montgomery T. Shaw, James R. Olson, and Mei Wei. "Influence of surface treatment and biomimetic hydroxyapatite coating on the mechanical properties of hydroxyapatite/poly (L-lactic acid) fibers." Journal of Biomaterials Applications 27, no. 6 (2013): 641-649. - 2013 - в издания, индексирани в Scopus и/или Web of Science

    Вид: пленарен доклад в международен форум, публикация в реферирано издание, индексирана в Scopus